PAG Asia 2024: MGI Tech launches whole workflow solution

PAG Asia 2024 took place from 5-7 June in Shenzhen, China. (Image source: Adobe Stock)

During this year's International Plant and Animal Genome Conference Asia (PAG Asia 2024), MGI Tech Co. Ltd. announced a highly efficient whole workflow solution for agricultural large-scale Low-pass whole genome sequencing (Low-pass WGS) based on its proprietary DNBSEQ platforms

The new solution consists of an automated full-process product portfolio designed for large-scale molecular breeding genotyping of agricultural diploid species. The full workflow covers extraction, library preparation, sequencing, and SNP & InDel calling.

The new MGIEasy Large-scale PCR-Free FS Library Prep Set for Low-pass WGS, available in two specifications, 96RXN and 384RXN, is designed specifically for Low-pass WGS applications with a new plate-based library preparation reagent module. Compared with common PCR-free library preparation sets on the market, this kit cuts the purification step and completes library construction in three easy steps, reducing the time and consumables required.

In combination with MGI's advanced automation platforms, the Low-pass WGS solution breaks through the limit on throughput as seen in ordinary library preparation. It utilises the fewer number of automated tools to match ultra-high throughput, as while maintaining a high degree of automation. As a result, large-scale library preparation can be done in a short time, at low cost, and with great automation friendliness.

For sequencing, the product bundles for high throughput and medium throughput Low-pass WGS feature the ultra-high-throughput DNBSEQ-T7 sequencer and the versatile DNBSEQ-G400 benchtop sequencer respectively, empowering large-scale agricultural genomics research projects in a short time.

"Since genome selection was widely used in agricultural breeding, genotyping tools went through several iterations, sequencing technology gradually shows its irreplaceable advantages," said Duncan Yu, president of MGI. "Low-pass WGS has been applied in both animal and plant breeding, but not without implementation challenges. Our new total solution for large-scale pig breeding addresses these user pain points and promises flexible automation needs, simplified library preparation, high throughput sequencing, and efficient data processing."

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